Dexter's Laboratory Issue #1 is the first issue of IDW Comics' Dexter's Laboratory comic book series. Unlike DC Comics' Dexter's Laboratory comics, the IDW comics consists of only four issues (not counting the unrelated crossovers that followed) and each issue is not a stand-alone story, instead they are part of an overarching storyline involving Dexter's attempts to bring back his sister Dee Dee.
After having had enough of Dee Dee's destructive antics, Dexter invents the Dreamwish-O-Tron 5000, a device that can make one's fondest dreams come true, which he plans to use to finally be rid of Dee Dee.
- Dee Dee
- Ultrabot 2000 (destroyed)
- Dynomutt X-90 (destroyed)
- Robo-Dexo 3000 (destroyed)
- This is not the first time Dexter has erased Dee Dee out of existence, having done so in "The Magic Moment" accidentally, although this is the first time he has done so willingly.